Indinavir Population Pharmacokinetics in Plasma and Cerebrospinal Fluid

Plasma and cerebrospinal fluid (CSF) indinavir concentrations were measured by high-performance liquid chromatography. The median concentration in plasma exceeded that in CSF 10-fold. The modeled CSF curve was flat at 155 nM, and the estimated ratio of the areas under the CSF and plasma concentratio...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Letendre, Scott L., Capparelli, Edmund V., Ellis, Ronald J., McCutchan, J. Allen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pharmacology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC90032/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10898694/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.44.8.2173-2175.2000
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