Heterogeneous Nuclear Ribonucleoprotein F Suppresses Angiotensinogen Gene Expression and Attenuates Hypertension and Kidney Injury in Diabetic Mice

We investigated the impact of heterogeneous nuclear ribonucleoprotein F (hnRNP F) overexpression on angiotensinogen (Agt) gene expression, hypertension, and renal proximal tubular cell (RPTC) injury in high-glucose milieu both in vivo and in vitro. Diabetic Akita transgenic (Tg) mice specifically ov...

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Main Authors: Lo, Chao-Sheng, Chang, Shiao-Ying, Chenier, Isabelle, Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao Ling, Chan, John S.D.
格式: Artigo
語言:Inglês
出版: American Diabetes Association 2012
主題:
Complications
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3447919/
https://ncbi.nlm.nih.gov/pubmed/22664958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1349
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