TARGETING STAT3 ABROGATES EGFR INHIBITOR RESISTANCE IN CANCER

PURPOSE: EGFR is upregulated in most epithelial cancers where signaling through EGFR contributes to cancer cell proliferation and survival. The limited clinical efficacy of EGFR inhibitors suggests that identification of resistance mechanisms may identify new pathways for therapeutic targeting. Sign...

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Detaylı Bibliyografya
Asıl Yazarlar: Sen, Malabika, Joyce, Sonali, Panahandeh, Mary, Li, Changyou, Thomas, Sufi M., Maxwell, Jessica, Wang, Lin, Gooding, William E., Johnson, Daniel E., Grandis, Jennifer R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445706/
https://ncbi.nlm.nih.gov/pubmed/22825581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-12-0792
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