Targeting TORC1/2 Enhances Sensitivity to EGFR Inhibitors in Head and Neck Cancer Preclinical Models

Head and neck squamous cell carcinoma (HNSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR) where treatments targeting EGFR have met with limited clinical success. Elucidation of the key downstream-pathways that remain activated in the setting of EGFR blockade may...

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Bibliographische Detailangaben
Hauptverfasser: Cassell, Andre, Freilino, Maria L, Lee, Jessica, Barr, Sharon, Wang, Lin, Panahandeh, Mary C, Thomas, Sufi M, Grandis, Jennifer R
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514742/
https://ncbi.nlm.nih.gov/pubmed/23226094
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