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Targeting TORC1/2 Enhances Sensitivity to EGFR Inhibitors in Head and Neck Cancer Preclinical Models

Head and neck squamous cell carcinoma (HNSCC) is characterized by overexpression of the epidermal growth factor receptor (EGFR) where treatments targeting EGFR have met with limited clinical success. Elucidation of the key downstream-pathways that remain activated in the setting of EGFR blockade may...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cassell, Andre, Freilino, Maria L, Lee, Jessica, Barr, Sharon, Wang, Lin, Panahandeh, Mary C, Thomas, Sufi M, Grandis, Jennifer R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Neoplasia Press Inc. 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514742/
https://ncbi.nlm.nih.gov/pubmed/23226094
Tagiau: Ychwanegu Tag
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