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Preclinical modeling of EGFR inhibitor resistance in head and neck cancer

The epidermal growth factor receptor (EGFR) is widely expressed in head and neck squamous cell carcinomas (HNSCC) and can activate many growth and survival pathways within tumor cells. Despite ubiquitous EGFR expression, therapies targeting the receptor are only modestly effective in the treatment o...

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Detalhes bibliográficos
Main Authors: Quesnelle, Kelly M., Wheeler, Sarah E., Ratay, Mary K., Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3414414/
https://ncbi.nlm.nih.gov/pubmed/22785204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.20846
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