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Anti-tumor mechanisms of targeting the PDK1 pathway in head and neck cancer

G-protein-coupled receptors (GPCRs) activate the epidermal growth factor receptor (EGFR) and mediate EGFR-independent signaling pathways to promote the growth of a variety of cancers including head and neck squamous cell carcinoma (HNSCC). Identification of the common signaling mechanisms involved i...

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Detalles Bibliográficos
Main Authors: Bhola, Neil E., Freilino, Maria L., Joyce, Sonali C., Sen, Malabika, Thomas, Sufi M., Sahu, Anirban, Cassell, Andre, Chen, Ching-Shih, Grandis, Jennifer R.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413198/
https://ncbi.nlm.nih.gov/pubmed/22491800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-11-0936
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