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Targeting GPCR-mediated p70S6K activity may improve head and neck cancer response to cetuximab

PURPOSE: EGFR overexpression is correlated with decreased survival in head and neck cancer (HNC) where the addition of EGFR inhibition to standard chemoradiation approaches has improved treatment responses. However, the basis for the limited efficacy of EGFR inhibitors in HNC is incompletely underst...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Bhola, Neil E., Thomas, Sufi M., Freilino, Maria, Joyce, Sonali, Sahu, Anirban, Maxwell, Jessica, Argiris, Athanassios, Seethala, Raja, Grandis, Jennifer R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149755/
https://ncbi.nlm.nih.gov/pubmed/21653688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-10-3406
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