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Serum Biomarker Modulation Following Molecular Targeting of Epidermal Growth Factor and Cycloxygenase Pathways: a Pilot Randomized Trial in Head and Neck Cancer
Targeting the epidermal growth factor receptor (EGFR) using the tyrosine kinase inhibitor (TKI) erlotinib has demonstrated activity in aerodigestive tract malignancies. Co-targeting of the G-protein-coupled receptor cyclooxygenase (COX) with EGFR inhibitors has shown promise in preclinical models an...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3462892/ https://ncbi.nlm.nih.gov/pubmed/22732263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2012.05.015 |
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