Serum Biomarker Modulation Following Molecular Targeting of Epidermal Growth Factor and Cycloxygenase Pathways: a Pilot Randomized Trial in Head and Neck Cancer

Targeting the epidermal growth factor receptor (EGFR) using the tyrosine kinase inhibitor (TKI) erlotinib has demonstrated activity in aerodigestive tract malignancies. Co-targeting of the G-protein-coupled receptor cyclooxygenase (COX) with EGFR inhibitors has shown promise in preclinical models an...

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Bibliografiset tiedot
Päätekijät: Moskowitz, Howard S., Gooding, William E., Thomas, Sufi M., Freilino, Maria L., Gross, Neil, Argiris, Athanassios, Grandis, Jennifer R., Ferris, Robert L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3462892/
https://ncbi.nlm.nih.gov/pubmed/22732263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.oraloncology.2012.05.015
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