Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

PURPOSE: Increased expression and/or activation of epidermal growth factor receptor (EGFR) is associated with tumor progression and poor prognosis in many cancers including head and neck squamous cell carcinoma (HNSCC). Src family kinases, including c-Src, mediate a variety of intra- or extracellula...

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Main Authors: Koppikar, Priya, Choi, Seung-Ho, Egloff, Ann Marie, Cai, Quan, Suzuki, Shinsuke, Freilino, Maria, Nozawa, Hiroshi, Thomas, Sufi M., Gooding, William E., Siegfried, Jill M., Grandis, Jennifer R.
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428119/
https://ncbi.nlm.nih.gov/pubmed/18594011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-5226
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