Combined inhibition of PLCγ-1 and c-Src abrogates Epidermal Growth Factor Receptor-mediated head and neck squamous cell carcinoma invasion

PURPOSE: Mortality from head and neck squamous cell carcinoma (HNSCC) is usually associated with locoregional invasion of the tumor into vital organs including the airway. Understanding the signaling mechanisms that abrogate HNSCC invasion may reveal novel therapeutic targets for intervention. The p...

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Main Authors: Nozawa, Hiroshi, Howell, Gina, Suzuki, Shinsuke, Zhang, Qing, Qi, Yanjun, Klein-Seetharaman, Judith, Wells, Alan, Grandis, Jennifer R, Thomas, Sufi M
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358699/
https://ncbi.nlm.nih.gov/pubmed/18594017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4857
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