Combined inhibition of PLCγ-1 and c-Src abrogates Epidermal Growth Factor Receptor-mediated head and neck squamous cell carcinoma invasion

PURPOSE: Mortality from head and neck squamous cell carcinoma (HNSCC) is usually associated with locoregional invasion of the tumor into vital organs including the airway. Understanding the signaling mechanisms that abrogate HNSCC invasion may reveal novel therapeutic targets for intervention. The p...

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Bibliografiske detaljer
Main Authors: Nozawa, Hiroshi, Howell, Gina, Suzuki, Shinsuke, Zhang, Qing, Qi, Yanjun, Klein-Seetharaman, Judith, Wells, Alan, Grandis, Jennifer R, Thomas, Sufi M
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3358699/
https://ncbi.nlm.nih.gov/pubmed/18594017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-4857
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