Dimerization and the effectiveness of ICAM-1 in mediating LFA-1-dependent adhesion
Dimeric intercellular adhesion molecule-1 (ICAM-1) binds more efficiently to lymphocyte function-associated antigen-1 (LFA-1) than monomeric ICAM-1. However, it is unknown whether dimerization enhances binding simply by providing two ligand-binding sites and thereby increasing avidity, or whether it...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2001
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC34438/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11391003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.121186998 |
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