Carregant...

Characterization of Isoenzyme-Selective Inhibitors of Human Sphingosine Kinases

Sphingosine kinases (SKs) are promising new therapeutic targets for cancer because they regulate the balance between pro-apoptotic ceramides and mitogenic sphingosine-1-phosphate. The functions of the two SK isoenzymes, SK1 and SK2, are not redundant, with genetic ablation of SK2 having more pronoun...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Gao, Peng, Peterson, Yuri K., Smith, Ryan A., Smith, Charles D.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3438171/
https://ncbi.nlm.nih.gov/pubmed/22970244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0044543
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!