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Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice
Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC343810/ https://ncbi.nlm.nih.gov/pubmed/14701729 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.550-560.2004 |
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