Early Glomerular Filtration Defect and Severe Renal Disease in Podocin-Deficient Mice

Podocytes are specialized epithelial cells covering the basement membrane of the glomerulus in the kidney. The molecular mechanisms underlying the role of podocytes in glomerular filtration are still largely unknown. We generated podocin-deficient (Nphs2(−/−)) mice to investigate the function of pod...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Roselli, Séverine, Heidet, Laurence, Sich, Mireille, Henger, Anna, Kretzler, Matthias, Gubler, Marie-Claire, Antignac, Corinne
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2004
विषय:
Mammalian Genetic Models with Minimal or Complex Phenotypes
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC343810/
https://ncbi.nlm.nih.gov/pubmed/14701729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.2.550-560.2004
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