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Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

We recently described an immunocompetent Syrian hamster model for oncolytic adenoviruses (Ads) that permits virus replication in tumor cells as well as some normal tissues. This model allows exploration of interactions between the virus, tumor, normal organs, and host immune system that could not be...

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Hlavní autoři: Thomas, Maria A, Spencer, Jacqueline F, Toth, Karoly, Sagartz, John E, Phillips, Nancy J, Wold, William SM
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437752/
https://ncbi.nlm.nih.gov/pubmed/18665155
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