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Immunosuppression Enhances Oncolytic Adenovirus Replication and Antitumor Efficacy in the Syrian Hamster Model

We recently described an immunocompetent Syrian hamster model for oncolytic adenoviruses (Ads) that permits virus replication in tumor cells as well as some normal tissues. This model allows exploration of interactions between the virus, tumor, normal organs, and host immune system that could not be...

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Detalhes bibliográficos
Main Authors: Thomas, Maria A, Spencer, Jacqueline F, Toth, Karoly, Sagartz, John E, Phillips, Nancy J, Wold, William SM
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3437752/
https://ncbi.nlm.nih.gov/pubmed/18665155
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