The role of cyclophosphamide in enhancing antitumor efficacy of an adenovirus oncolytic vector in subcutaneous Syrian hamster tumors

We have previously reported that intratumoral injection of VRX-007—an Ad5-based vector overexpressing ADP (Adenovirus Death Protein)—can suppress the growth of subcutaneous HaK (hamster renal cancer) tumors. VRX-007 replication and tumor growth inhibition are enhanced when the hamsters are immunosup...

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Autores principales: Young, Brittany A., Spencer, Jacqueline F., Ying, Baoling, Tollefson, Ann E., Toth, Karoly, Wold, William S. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778155/
https://ncbi.nlm.nih.gov/pubmed/23928731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2013.49
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