Methylglyoxal Activates Nociceptors through Transient Receptor Potential Channel A1 (TRPA1): A POSSIBLE MECHANISM OF METABOLIC NEUROPATHIES

Neuropathic pain can develop as an agonizing sequela of diabetes mellitus and chronic uremia. A chemical link between both conditions of altered metabolism is the highly reactive compound methylglyoxal (MG), which accumulates in all cells, in particular neurons, and leaks into plasma as an index of...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Eberhardt, Mirjam J., Filipovic, Milos R., Leffler, Andreas, de la Roche, Jeanne, Kistner, Katrin, Fischer, Michael J., Fleming, Thomas, Zimmermann, Katharina, Ivanovic-Burmazovic, Ivana, Nawroth, Peter P., Bierhaus, Angelika, Reeh, Peter W., Sauer, Susanne K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
Matèries:
Neurobiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3436587/
https://ncbi.nlm.nih.gov/pubmed/22740698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.328674
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars