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An image-based screen identifies a small molecule regulator of megakaryopoiesis

Molecules that control the lineage commitment of hematopoietic stem cells (HSCs) may allow the expansion of enriched progenitor populations for both research and therapeutic uses. In an effort to better understand and control the differentiation of HSCs to megakaryocytes, we carried out an image-bas...

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Hlavní autoři: Boitano, Anthony E., de Lichtervelde, Lorenzo, Snead, Jennifer L., Cooke, Michael P., Schultz, Peter G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435220/
https://ncbi.nlm.nih.gov/pubmed/22891346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212545109
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