A small molecule screen to identify regulators of let-7 targets

The let-7 family of miRNAs has been shown to be crucial in many aspects of biology, from the regulation of developmental timing to cancer. The available methods to regulate this family of miRNAs have so far been mostly genetic and therefore not easily performed experimentally. Here, we describe a sm...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cinkornpumin, J., Roos, M., Nguyen, L., Liu, Xiaoguang, Gaeta, X., Lin, S., Chan, D. N., Liu, A., Gregory, R. I., Jung, M., Chute, J., Zhu, H., Lowry, W. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698460/
https://ncbi.nlm.nih.gov/pubmed/29162914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16258-9
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