A small molecule screen to identify regulators of let-7 targets

The let-7 family of miRNAs has been shown to be crucial in many aspects of biology, from the regulation of developmental timing to cancer. The available methods to regulate this family of miRNAs have so far been mostly genetic and therefore not easily performed experimentally. Here, we describe a sm...

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Udgivet i:Sci Rep
Main Authors: Cinkornpumin, J., Roos, M., Nguyen, L., Liu, Xiaoguang, Gaeta, X., Lin, S., Chan, D. N., Liu, A., Gregory, R. I., Jung, M., Chute, J., Zhu, H., Lowry, W. E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698460/
https://ncbi.nlm.nih.gov/pubmed/29162914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16258-9
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