Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

Neutrophil chemotaxis plays an essential role in innate immunity, but the underlying cellular mechanism is still not fully characterized. Here, using a small-molecule functional screening, we identified NADPH oxidase–dependent reactive oxygen species as key regulators of neutrophil chemotactic migra...

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Detalhes bibliográficos
Main Authors: Hattori, Hidenori, Subramanian, Kulandayan K., Sakai, Jiro, Jia, Yonghui, Li, Yitang, Porter, Timothy F., Loison, Fabien, Sarraj, Bara, Kasorn, Anongnard, Jo, Hakryul, Blanchard, Catlyn, Zirkle, Dorothy, McDonald, Douglas, Pai, Sung-Yun, Serhan, Charles N., Luo, Hongbo R.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840460/
https://ncbi.nlm.nih.gov/pubmed/20142487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914351107
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