Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

Neutrophil chemotaxis plays an essential role in innate immunity, but the underlying cellular mechanism is still not fully characterized. Here, using a small-molecule functional screening, we identified NADPH oxidase–dependent reactive oxygen species as key regulators of neutrophil chemotactic migra...

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Detaylı Bibliyografya
Asıl Yazarlar: Hattori, Hidenori, Subramanian, Kulandayan K., Sakai, Jiro, Jia, Yonghui, Li, Yitang, Porter, Timothy F., Loison, Fabien, Sarraj, Bara, Kasorn, Anongnard, Jo, Hakryul, Blanchard, Catlyn, Zirkle, Dorothy, McDonald, Douglas, Pai, Sung-Yun, Serhan, Charles N., Luo, Hongbo R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2010
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840460/
https://ncbi.nlm.nih.gov/pubmed/20142487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914351107
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