RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells

All-trans retinoic acid (ATRA) has been widely used in differentiation therapy for acute promyelocytic leukemia (APL). ATRA binds to retinoic acid receptor (RAR) and triggers the formation of the transcription coactivator complex, which leads to changes in gene expression, APL cell-cycle arrest and...

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Detalhes bibliográficos
Main Authors: Hattori, Hidenori, Zhang, Xueqing, Jia, Yonghui, Subramanian, Kulandayan K., Jo, Hakryul, Loison, Fabien, Newburger, Peter E., Luo, Hongbo R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1924478/
https://ncbi.nlm.nih.gov/pubmed/17420285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-059048
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