Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis

Neutrophil chemotaxis plays an essential role in innate immunity, but the underlying cellular mechanism is still not fully characterized. Here, using a small-molecule functional screening, we identified NADPH oxidase–dependent reactive oxygen species as key regulators of neutrophil chemotactic migra...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hattori, Hidenori, Subramanian, Kulandayan K., Sakai, Jiro, Jia, Yonghui, Li, Yitang, Porter, Timothy F., Loison, Fabien, Sarraj, Bara, Kasorn, Anongnard, Jo, Hakryul, Blanchard, Catlyn, Zirkle, Dorothy, McDonald, Douglas, Pai, Sung-Yun, Serhan, Charles N., Luo, Hongbo R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2010
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2840460/
https://ncbi.nlm.nih.gov/pubmed/20142487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914351107
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