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Tau promotes neurodegeneration via DRP1 mislocalization in vivo

Mitochondrial abnormalities have been documented in Alzheimer’s disease and related neurodegenerative disorders, but the causal relationship between mitochondrial changes and neurodegeneration, as well as the specific mechanisms promoting mitochondrial dysfunction, are not clear. Here we find that e...

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Bibliografiske detaljer
Main Authors: DuBoff, Brian, Götz, Jürgen, Feany, Mel B.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428596/
https://ncbi.nlm.nih.gov/pubmed/22920254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.06.026
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