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Tau promotes neurodegeneration through global chromatin relaxation
The microtubule-associated protein tau is involved in a number of neurodegenerative disorders, including Alzheimer’s disease (AD). Previous studies link oxidative stress and subsequent DNA damage to neuronal death in AD and related tauopathies. Since DNA damage can significantly alter chromatin stru...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4012297/ https://ncbi.nlm.nih.gov/pubmed/24464041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3639 |
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