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Connecting the Dots Between Tau Dysfunction and Neurodegeneration

Tauopathies are devastating and ultimately fatal neurodegenerative diseases, which are histopathologically defined by insoluble filamentous deposits of abnormally phosphorylated tau protein within neurons and glia. Identifying the causes of abnormal tau phosphorylation and subsequent aggregation has...

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Detalhes bibliográficos
Publicado no:Trends Cell Biol
Main Authors: Frost, Bess, Götz, Jürgen, Feany, Mel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275400/
https://ncbi.nlm.nih.gov/pubmed/25172552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.07.005
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