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Connecting the Dots Between Tau Dysfunction and Neurodegeneration

Tauopathies are devastating and ultimately fatal neurodegenerative diseases, which are histopathologically defined by insoluble filamentous deposits of abnormally phosphorylated tau protein within neurons and glia. Identifying the causes of abnormal tau phosphorylation and subsequent aggregation has...

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Publicat a:Trends Cell Biol
Autors principals: Frost, Bess, Götz, Jürgen, Feany, Mel B.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275400/
https://ncbi.nlm.nih.gov/pubmed/25172552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.07.005
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