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Connecting the Dots Between Tau Dysfunction and Neurodegeneration

Tauopathies are devastating and ultimately fatal neurodegenerative diseases, which are histopathologically defined by insoluble filamentous deposits of abnormally phosphorylated tau protein within neurons and glia. Identifying the causes of abnormal tau phosphorylation and subsequent aggregation has...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Trends Cell Biol
Main Authors: Frost, Bess, Götz, Jürgen, Feany, Mel B.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275400/
https://ncbi.nlm.nih.gov/pubmed/25172552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcb.2014.07.005
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