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Tau promotes neurodegeneration via DRP1 mislocalization in vivo

Mitochondrial abnormalities have been documented in Alzheimer’s disease and related neurodegenerative disorders, but the causal relationship between mitochondrial changes and neurodegeneration, as well as the specific mechanisms promoting mitochondrial dysfunction, are not clear. Here we find that e...

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Main Authors: DuBoff, Brian, Götz, Jürgen, Feany, Mel B.
格式: Artigo
語言:Inglês
出版: 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428596/
https://ncbi.nlm.nih.gov/pubmed/22920254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2012.06.026
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