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Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing

A precise molecular identification of transmitted hepatitis C virus (HCV) genomes could illuminate key aspects of transmission biology, immunopathogenesis and natural history. We used single genome sequencing of 2,922 half or quarter genomes from plasma viral RNA to identify transmitted/founder (T/F...

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主要な著者: Li, Hui, Stoddard, Mark B., Wang, Shuyi, Blair, Lily M., Giorgi, Elena E., Parrish, Erica H., Learn, Gerald H., Hraber, Peter, Goepfert, Paul A., Saag, Michael S., Denny, Thomas N., Haynes, Barton F., Hahn, Beatrice H., Ribeiro, Ruy M., Perelson, Alan S., Korber, Bette T., Bhattacharya, Tanmoy, Shaw, George M.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426529/
https://ncbi.nlm.nih.gov/pubmed/22927816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002880
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