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Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing

A precise molecular identification of transmitted hepatitis C virus (HCV) genomes could illuminate key aspects of transmission biology, immunopathogenesis and natural history. We used single genome sequencing of 2,922 half or quarter genomes from plasma viral RNA to identify transmitted/founder (T/F...

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Bibliografski detalji
Glavni autori: Li, Hui, Stoddard, Mark B., Wang, Shuyi, Blair, Lily M., Giorgi, Elena E., Parrish, Erica H., Learn, Gerald H., Hraber, Peter, Goepfert, Paul A., Saag, Michael S., Denny, Thomas N., Haynes, Barton F., Hahn, Beatrice H., Ribeiro, Ruy M., Perelson, Alan S., Korber, Bette T., Bhattacharya, Tanmoy, Shaw, George M.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426529/
https://ncbi.nlm.nih.gov/pubmed/22927816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002880
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