Single-Genome Sequencing of Hepatitis C Virus in Donor-Recipient Pairs Distinguishes Modes and Models of Virus Transmission and Early Diversification

Despite the recent development of highly effective anti-hepatitis C virus (HCV) drugs, the global burden of this pathogen remains immense. Control or eradication of HCV will likely require the broad application of antiviral drugs and development of an effective vaccine. A precise molecular identific...

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Bibliographic Details
Published in:J Virol
Main Authors: Li, Hui, Stoddard, Mark B., Wang, Shuyi, Giorgi, Elena E., Blair, Lily M., Learn, Gerald H., Hahn, Beatrice H., Alter, Harvey J., Busch, Michael P., Fierer, Daniel S., Ribeiro, Ruy M., Perelson, Alan S., Bhattacharya, Tanmoy, Shaw, George M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genetic Diversity and Evolution
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4702571/
https://ncbi.nlm.nih.gov/pubmed/26468546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02156-15
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