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Transmission of Multiple HIV-1 Subtype C Transmitted/founder Viruses into the Same Recipients Was not Determined by Modest Phenotypic Differences

A severe bottleneck exists during HIV-1 mucosal transmission. However, viral properties that determine HIV-1 transmissibility are not fully elucidated. We identified multiple transmitted/founder (T/F) viruses in six HIV-1-infected subjects by analyzing whole genome sequences. Comparison of biologica...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Song, Hongshuo, Hora, Bhavna, Giorgi, Elena E., Kumar, Amit, Cai, Fangping, Bhattacharya, Tanmoy, Perelson, Alan S., Gao, Feng
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5133561/
https://ncbi.nlm.nih.gov/pubmed/27909304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep38130
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