Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome

BACKGROUND: A modest change in HIV-1 fitness can have a significant impact on viral quasispecies evolution and viral pathogenesis, transmission and disease progression. To determine the impact of immune escape mutations selected by cytotoxic T lymphocytes (CTL) on viral fitness in the context of the...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Song, Hongshuo, Pavlicek, Jeffrey W, Cai, Fangping, Bhattacharya, Tanmoy, Li, Hui, Iyer, Shilpa S, Bar, Katharine J, Decker, Julie M, Goonetilleke, Nilu, Liu, Michael KP, Berg, Anna, Hora, Bhavna, Drinker, Mark S, Eudailey, Josh, Pickeral, Joy, Moody, M Anthony, Ferrari, Guido, McMichael, Andrew, Perelson, Alan S, Shaw, George M, Hahn, Beatrice H, Haynes, Barton F, Gao, Feng
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496648/
https://ncbi.nlm.nih.gov/pubmed/23110705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-9-89
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires