Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

Hepatitis C virus (HCV) is present in the host with multiple variants generated by its error prone RNA-dependent RNA polymerase. Little is known about the initial viral diversification and the viral life cycle processes that influence diversity. We studied the diversification of HCV during acute inf...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Ribeiro, Ruy M., Li, Hui, Wang, Shuyi, Stoddard, Mark B., Learn, Gerald H., Korber, Bette T., Bhattacharya, Tanmoy, Guedj, Jeremie, Parrish, Erica H., Hahn, Beatrice H., Shaw, George M., Perelson, Alan S.
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2012
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426522/
https://ncbi.nlm.nih.gov/pubmed/22927817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002881
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