Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

Hepatitis C virus (HCV) is present in the host with multiple variants generated by its error prone RNA-dependent RNA polymerase. Little is known about the initial viral diversification and the viral life cycle processes that influence diversity. We studied the diversification of HCV during acute inf...

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書誌詳細
主要な著者: Ribeiro, Ruy M., Li, Hui, Wang, Shuyi, Stoddard, Mark B., Learn, Gerald H., Korber, Bette T., Bhattacharya, Tanmoy, Guedj, Jeremie, Parrish, Erica H., Hahn, Beatrice H., Shaw, George M., Perelson, Alan S.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426522/
https://ncbi.nlm.nih.gov/pubmed/22927817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002881
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