Elucidation of Hepatitis C Virus Transmission and Early Diversification by Single Genome Sequencing

A precise molecular identification of transmitted hepatitis C virus (HCV) genomes could illuminate key aspects of transmission biology, immunopathogenesis and natural history. We used single genome sequencing of 2,922 half or quarter genomes from plasma viral RNA to identify transmitted/founder (T/F...

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Bibliografische gegevens
Hoofdauteurs: Li, Hui, Stoddard, Mark B., Wang, Shuyi, Blair, Lily M., Giorgi, Elena E., Parrish, Erica H., Learn, Gerald H., Hraber, Peter, Goepfert, Paul A., Saag, Michael S., Denny, Thomas N., Haynes, Barton F., Hahn, Beatrice H., Ribeiro, Ruy M., Perelson, Alan S., Korber, Bette T., Bhattacharya, Tanmoy, Shaw, George M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426529/
https://ncbi.nlm.nih.gov/pubmed/22927816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002880
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