Estimating time since infection in early homogeneous HIV-1 samples using a poisson model

BACKGROUND: The occurrence of a genetic bottleneck in HIV sexual or mother-to-infant transmission has been well documented. This results in a majority of new infections being homogeneous, i.e., initiated by a single genetic strain. Early after infection, prior to the onset of the host immune respons...

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Huvudupphovsmän: Giorgi, Elena E, Funkhouser, Bob, Athreya, Gayathri, Perelson, Alan S, Korber, Bette T, Bhattacharya, Tanmoy
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975664/
https://ncbi.nlm.nih.gov/pubmed/20973976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-532
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