Lack of toxicity of a STAT3 decoy oligonucleotide

BACKGROUND: STAT3 overexpression has been detected in several cancers including head and neck squamous cell carcinoma (HNSCC). Previous studies using intratumoral administration of a STAT3 decoy oligonucleotide that abrogates STAT3-mediated gene transcription in preclinical cancer models have demons...

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Bibliografiske detaljer
Main Authors: Sen, Malabika, Tosca, Patricia J., Zwayer, Christa, Ryan, Michael J., Johnson, Jerry D., Knostman, Katherine A. B., Giclas, Patricia C., Peggins, James O., Tomaszewski, Joseph E., McMurray, Timothy P., Li, Changyou, Leibowitz, Michael S., Ferris, Robert L., Gooding, William E., Thomas, Sufi M., Johnson, Daniel E., Grandis, Jennifer R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422883/
https://ncbi.nlm.nih.gov/pubmed/18766340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-008-0823-6
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