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Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome

The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available for eliminating gene function. Here we present simple and efficient methods for inducing, detecting, and recoveri...

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Bibliografski detalji
Glavni autori: Dahlem, Timothy J., Hoshijima, Kazuyuki, Jurynec, Michael J., Gunther, Derrick, Starker, Colby G., Locke, Alexandra S., Weis, Allison M., Voytas, Daniel F., Grunwald, David Jonah
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420959/
https://ncbi.nlm.nih.gov/pubmed/22916025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002861
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