Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome

The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available for eliminating gene function. Here we present simple and efficient methods for inducing, detecting, and recoveri...

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Main Authors: Dahlem, Timothy J., Hoshijima, Kazuyuki, Jurynec, Michael J., Gunther, Derrick, Starker, Colby G., Locke, Alexandra S., Weis, Allison M., Voytas, Daniel F., Grunwald, David Jonah
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420959/
https://ncbi.nlm.nih.gov/pubmed/22916025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002861
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