Simple Methods for Generating and Detecting Locus-Specific Mutations Induced with TALENs in the Zebrafish Genome

The zebrafish is a powerful experimental system for uncovering gene function in vertebrate organisms. Nevertheless, studies in the zebrafish have been limited by the approaches available for eliminating gene function. Here we present simple and efficient methods for inducing, detecting, and recoveri...

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Main Authors: Dahlem, Timothy J., Hoshijima, Kazuyuki, Jurynec, Michael J., Gunther, Derrick, Starker, Colby G., Locke, Alexandra S., Weis, Allison M., Voytas, Daniel F., Grunwald, David Jonah
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420959/
https://ncbi.nlm.nih.gov/pubmed/22916025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002861
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