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Precise Editing of the Zebrafish Genome Made Simple and Efficient
We present simple and efficient methods for creating heritable modifications of the zebrafish genome. Precisely modified alleles are generated by homologous recombination between the host genome and dsDNA donor molecules, stimulated by the induction of chromosomally targeted DSBs. Several kilobase-l...
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| Publicado no: | Dev Cell |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4806538/ https://ncbi.nlm.nih.gov/pubmed/27003937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2016.02.015 |
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