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Precise and efficient genome editing in zebrafish using the CRISPR/Cas9 system

The introduction of engineered site-specific DNA endonucleases has brought precise genome editing in many model organisms and human cells into the realm of possibility. In zebrafish, loss-of-function alleles have been successfully produced; however, germ line transmission of functional targeted knoc...

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Foilsithe in:Development
Main Authors: Irion, Uwe, Krauss, Jana, Nüsslein-Volhard, Christiane
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Company of Biologists 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299274/
https://ncbi.nlm.nih.gov/pubmed/25411213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.115584
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