Systematic genome editing of the genes on zebrafish Chromosome 1 by CRISPR/Cas9

Genome editing by the well-established CRISPR/Cas9 technology has greatly facilitated our understanding of many biological processes. However, a complete whole-genome knockout for any species or model organism has rarely been achieved. Here, we performed a systematic knockout of all the genes (1333)...

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Bibliografiske detaljer
Udgivet i:Genome Res
Main Authors: Sun, Yonghua, Zhang, Bo, Luo, Lingfei, Shi, De-Li, Wang, Han, Cui, Zongbin, Huang, Honghui, Cao, Ying, Shu, Xiaodong, Zhang, Wenqing, Zhou, Jianfeng, Li, Yun, Du, Jiulin, Zhao, Qingshun, Chen, Jun, Zhong, Hanbing, Zhong, Tao P., Li, Li, Xiong, Jing-Wei, Peng, Jinrong, Xiao, Wuhan, Zhang, Jian, Yao, Jihua, Yin, Zhan, Mo, Xianming, Peng, Gang, Zhu, Jun, Chen, Yan, Zhou, Yong, Liu, Dong, Pan, Weijun, Zhang, Yiyue, Ruan, Hua, Liu, Feng, Zhu, Zuoyan, Meng, Anming, The ZAKOC Consortium
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2020
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961580/
https://ncbi.nlm.nih.gov/pubmed/31831591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.248559.119
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