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Targeting Human MicroRNA Genes Using Engineered Tal-Effector Nucleases (TALENs)

MicroRNAs (miRNAs) have quickly emerged as important regulators of mammalian physiology owing to their precise control over the expression of critical protein coding genes. Despite significant progress in our understanding of how miRNAs function in mice, there remains a fundamental need to be able t...

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Detalhes bibliográficos
Main Authors: Hu, Ruozhen, Wallace, Jared, Dahlem, Timothy J., Grunwald, David Jonah, O'Connell, Ryan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3646762/
https://ncbi.nlm.nih.gov/pubmed/23667577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063074
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