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New highly sensitive rodent and human tests for soluble amyloid precursor protein alpha quantification: preclinical and clinical applications in Alzheimer’s disease

BACKGROUND: Amyloid precursor protein (APP), a key molecule in Alzheimer’s disease (AD), is metabolized in two alternative cleavages, generating either the amyloidogenic peptides involved in AD pathology or the soluble form of APP (sAPPα). The level of amyloidogenic peptides in human cerebrospinal f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rose, Christiane, Peoc’h, Katell, Chasseigneaux, Stéphanie, Paquet, Claire, Dumurgier, Julien, Bourasset, Fanchon, Calon, Frédéric, Laplanche, Jean-Louis, Hugon, Jacques, Allinquant, Bernadette
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BioMed Central 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418197/
https://ncbi.nlm.nih.gov/pubmed/22824057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-84
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