Cerebrospinal fluid amyloid-β 42/40 ratio in clinical setting of memory centers: a multicentric study

INTRODUCTION: The cerebrospinal fluid (CSF) biomarkers amyloid-β (Aβ), tau and phosphorylated tau (p-tau181) are now used for the diagnosis of Alzheimer’s disease (AD). Aβ40 is the most abundant Aβ peptide isoform in the CSF, and the Aβ 42/40 ratio has been proposed to better reflect brain amyloid p...

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Enregistré dans:
Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Dumurgier, Julien, Schraen, Susanna, Gabelle, Audrey, Vercruysse, Olivier, Bombois, Stéphanie, Laplanche, Jean-Louis, Peoc’h, Katell, Sablonnière, Bernard, Kastanenka, Ksenia V, Delaby, Constance, Pasquier, Florence, Touchon, Jacques, Hugon, Jacques, Paquet, Claire, Lehmann, Sylvain
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4450486/
https://ncbi.nlm.nih.gov/pubmed/26034513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0114-5
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