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Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y(6) nucleotide receptors

The physiological role of the P2Y(6) nucleotide receptor may involve cardiovascular, immune and digestive functions based on the receptor tissue distribution, and selective antagonists for this receptor are lacking. We have synthesized a series of symmetric aryl diisothiocyanate derivatives and exam...

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Bibliografische gegevens
Hoofdauteurs: Mamedova, Liaman K., Joshi, Bhalchandra V., Gao, Zhan-Guo, von Kügelgen, Ivar, Jacobson, Kenneth A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2004
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3413726/
https://ncbi.nlm.nih.gov/pubmed/15081875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2004.01.011
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