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2,2′-Pyridylisatogen tosylate antagonizes P2Y(1) receptor signaling without affecting nucleotide binding
The effect of 2,2′-pyridylisatogen tosylate (PIT) on the human P2Y(1) receptor and on other recombinant P2Y receptors has been studied. We first examined the modulation by PIT of the agonist-induced accumulation of inositol phosphates. PIT blocked 2-methylthio-ADP (2-MeSADP)-induced accumulation of...
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| Publicado no: | Biochem Pharmacol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4372108/ https://ncbi.nlm.nih.gov/pubmed/15193995 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2004.02.039 |
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